VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Blue-and-yellow macaw

Scientific Name: Ara ararauna

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Sauropsida-> Sauria-> Archelosauria-> Archosauria-> Dinosauria-> Saurischia-> Theropoda-> Coelurosauria-> Aves-> Neognathae-> Psittaciformes-> Psittacidae-> Ara

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Influenza A virus

Family: Orthomyxoviridae

Receptor: EGFR

Receptor EGFR information

Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_0063 2021.04 iDrop PBMC Normal 5709 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of EGFR in human tissues   [NCBI]

Expression: Broad expression in placenta (RPKM 36.6), skin (RPKM 15.6) and 22 other tissues?

Protein expression of EGFR in human tissues   [Proteinatlas]